32 articles - From Friday Nov 14 2025 to Friday Nov 21 2025
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
meta-analyses and systematic reviews
| Pancreatology |
|---|
| Impact of pancreatic steatosis on risk of Post-ERCP pancreatitis: Systematic review and meta-analysis.
There was a non-significant trend toward increased odds of severe PEP with PS (OR 2.17, 95 % CI 0.65-7.25; I 2 = 0 %) CONCLUSIONS: PS appears to be a significant risk factor for the PEP and may help improve risk stratification before ERCP. Nevertheless, further large-scale prospective studies are needed to validate our results. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
|---|
| Association between hemoglobin levels and mild cognitive impairment in generally healthy European community-dwelling older adults: a three-year prospective analysis of the DO-HEALTH trial.
Baseline hemoglobin levels above 130 g/L were associated with reduced odds of MCI over three years. While this study does not establish causality, it suggests further investigations in monitoring and managing hemoglobin levels, even in generally healthy older adults. TRIAL REGISTRATION |
| Environmental enteric dysfunction, systemic inflammation, growth hormones, and linear growth in infants in western Kenya: a prospective observational cohort study.
Targeting young infants with environmental enteric dysfunction, and especially increased gut permeability, may prevent or ameliorate chronic systemic inflammation and improve growth and development in infants in western Kenya. The PROSYNK trial was registered at the Pan African Clinical Trials Registry ( as PACTR202003893276712 ( |
| Human milk composition is associated with maternal overweight/obesity and low milk supply, with implications for infant weight outcomes: a cross-sectional study.
Maternal OW influences HM composition and infant milk intake. LMS impacts infant weight gain by limiting milk volume, underscoring the importance of timely LMS detection to ensure adequate infant nutrition. |
| Nutritional adequacy of the EAT-Lancet planetary health diet: cross-sectional analyses of the United Kingdom National Diet and Nutrition Survey.
Nutritional adequacy was either better or unchanged with greater alignment to the PHD, suggesting that the PHD is unlikely to present concerns of nutritional inadequacy at the population level in the UK. |
| SYNERGIES BETWEEN FOOD BIODIVERSITY, PROCESSING LEVELS, AND THE EAT-LANCET DIET FOR NUTRIENT ADEQUACY AND ENVIRONMENTAL SUSTAINABILITY: A MULTI-OBJECTIVE OPTIMIZATION USING THE EPIC COHORT.
Diets that adhere to the EAT-Lancet diet, are more biodiverse, and prioritize unprocessed and minimally processed foods over UPFs, have the potential to synergistically enhance nutrient adequacy while minimizing environmental impacts. These findings suggest that moderate improvements across multiple dietary dimensions simultaneously can achieve meaningful gains in both nutritional adequacy and environmental sustainability. |
| The Effect of Consuming Diets Containing Beef Compared with Plant-Based Beef Substitute on Human Milk Composition in the Study of nUtrition in Postpartum and EaRly life (SUPER) Randomized Crossover Feeding Trial.
Replacing beef with plant-based UPF changed human milk fatty acid composition, reducing LCPUFAs and increasing tropical oil-derived saturated fats. These shifts may have implications for infant neurodevelopment and immune function, highlighting the need to distinguish between nutrient-equivalent and biologically equivalent foods in postpartum dietary guidance. |
| Inflamm Bowel Dis |
| Association of Spondyloarthritis With Chronic Opioid Use in Inflammatory Bowel Disease: A Nationwide Danish Cohort Study.
and relevance In this nationwide cohort, SpA was strongly associated with chronic opioid use in patients diagnosed with IBD. These findings highlight IBD+SpA as a high-risk phenotype warranting early identification and multidisciplinary pain management. |
| Exploring Gut Mucosal Microbiota to Distinguish Crohn's Disease from Intestinal Tuberculosis.
Significant differences were noted in the composition and predicted function of the gut microbiota between the two conditions. Microbial dysbiosis was more severe in intestinal tuberculosis than in Crohn's disease and could differentiate between the two conditions with good accuracy. |
| Fibroblast-Mediated MMP2 Contribution to Nonresponse in Anti-TNFα Therapy for Crohn's Disease.
This study highlights the association of pathogenic fibroblasts and ECM remodeling in anti-TNFα therapy failure, identifies MMP2 as a potential target, and suggests that combination therapy may offer a potential strategy for patients with treatment resistance. |
| Nationwide Analysis of Food Insecurity among Individuals with Inflammatory Bowel Disease in the United States.
Individuals with IBD face a persistently higher risk of food insecurity. Some of the most important predictors included being non-Hispanic Black, being uninsured or having Medicaid insurance, and using SNAP. Clinicians should regularly screen patients with IBD for food insecurity and address it through a multidisciplinary approach, involving dietitians and social workers to enhance patient care and outcomes. |
| Real-World Effectiveness of and Optimization Strategies for Mirikizumab in Pediatric Ulcerative Colitis: A Prospective, Observational Study.
MIRI can induce and sustain CR in pediatric UC, particularly when early optimization strategies are applied. These findings highlight IUS as a useful surrogate for mucosal healing and support MIRI as a promising, adaptable, and safe therapeutic option in pediatric UC. |
| The Importance of Treatment Timing and Positioning in IBD.
This commentary examines the progressive decline in biologic efficacy in inflammatory bowel disease, highlighting pharmacologic, immunologic, and cellular mechanisms of resistance. It advocates for early, biomarker-guided, and mechanistically informed sequencing to preserve long-term therapeutic response and overcome the emerging "therapeutic ceiling." |
| The Paradox of NET Involvement in the Pathogenesis of Inflammatory Bowel Disease.
Conversely, we consider how inflammation-driven changes in neutrophil activation, phenotype and immunometabolism can cause dysregulation in NET production and clearance and lead to harmful intestinal effects that can prolong intestinal and chronic inflammation in IBD. Specifically, we explore how uncontrolled NET production can damage intestinal epithelial integrity, increase bacterial translocation and increase thromboembolic risk, ultimately linking NETs to the pro-inflammatory pathogenesis of IBD. |
| J Crohns Colitis |
| Addition of pulse corticosteroids to oral prednisone in moderately active ulcerative colitis: A randomized, multicentre, open-label study by GETECCU.
The addition of three pulses of high-dose corticosteroids to a conventional regimen of oral prednisone does not improve medium and long-term clinical outcomes in moderately active UC. |
| Automated real-time imaging of intestinal barrier integrity and molecular profiling for early outcome prediction in inflammatory bowel disease - Endo-Histo-Barrier-Omics study.
Automated advanced imaging enables real-time barrier assessment in IBD and correlates with markers of epithelial and vascular barrier impairment. AI integration can enhance standardization toward broader clinical applicability. |
| Frequency of dysplasia in endoscopically resected pseudopolyps in inflammatory bowel diseases.
Dysplasia was found in 12% of pseudopolypoid lesions, challenging the assumption that they are uniformly benign. Endoscopic features such as heterogeneous pit pattern and absence of ulceration may aid in identifying high-risk lesions. These results highlight the diagnostic uncertainty surrounding pseudopolyps in IBD and call for careful endoscopic assessment rather than routine resection. |
| Modified-2-stage versus 3-stage approach in ileoanal pouch surgery for Ulcerative Colitis.
Both approaches have comparable high stoma-free rates at the end of follow-up. Modified-2-stage avoids a temporary stoma in more than 75% of patients, but has a significantly higher rate of anastomotic leakages. Active and early surveillance of the anastomosis after 3-stage procedures could improve postoperative outcomes in this group. |
| Serum Protein Profiles Differ with Adalimumab and Ustekinumab Treatment in Moderately to Severely Active Crohn's Disease.
Although patients receiving either adalimumab or ustekinumab reached similar rates of clinical remission at Week 52, the two therapies resulted in unique serum proteomic expression profiles reflecting mechanistic differences. Long-term treatment data is necessary to understand how differences in therapeutic mechanisms are associated with maintenance of remission and changes in patient reported outcomes in the context of inflammatory biomarkers. |
| Liver Transpl |
| Associations between socioeconomic factors and post-liver transplant mortality across recovery phases.
These findings demonstrate that socioeconomic vulnerability after LT is not fixed but evolves over time. This study introduces a time-resolved framework that identifies when SES factors first become consequential, highlighting actionable windows for targeted interventions to reduce inequities in post-transplant care. |
| Improved liver transplant outcomes for patients with hilar cholangiocarcinoma following implementation of the MMAT-3 policy.
However, although significantly improved, waitlist mortality remained higher in hCCA patients compared to HCC patients (three-year dropout: 17.6% vs 14.%, p=0.02). Under the MMaT policy, hCCA patients have improved access to LT with improved waitlist survival. |
| Pancreatology |
| Mapping of lymph node metastasis in nonfunctional pancreatic neuroendocrine tumors: A retrospective analysis of 455 patients.
Lymph node metastases are uncommon in pNETs 2 cm, lymphadenectomy should be tailored to metastasis risk at specific stations. |
| Types of pancreatic lesions and the mutational landscape of the VHL gene in patients with von Hippel-Lindau disease.
Pancreatic lesions are common in VHL disease. Mutations in codons 161 and 167 are hotspots in patients with pancreatic lesions, particularly NETs. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Inflamm Bowel Dis |
|---|
| Barriers and Opportunities for Resilience Programs in IBD: Insights From the SMART Project. |
| Breaking Free from Corticosteroids in Crohn's Disease.
This editorial discusses the post-hoc analysis by Dubinsky et al evaluating upadacitinib's efficacy and safety by baseline corticosteroid use in Crohn's disease, highlighting its corticosteroid-sparing potential, the need for standardized tapering in trials, and the implications for achieving durable corticosteroid-free remission. |
| Looking Beyond the Mucosa: A New Scoring System for Mesenteric Fat in Intestinal Ultrasound. |
| Pancreatology |
| ENDPAC model for defining a high-risk group for pancreatic cancer: Strengths, limitations and the way forward. |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Inflamm Bowel Dis |
|---|
| Early-Life Body Mass Index and Inflammatory Bowel Disease Risk: A Scandinavian Birth Cohort Study. |
| Pancreatology |
| Proceeding with liver transplantation in acute non-necrotizing pancreatitis: A 10-year propensity-matched cohort study. |
Letters to the editors and authors’ replies
| Inflamm Bowel Dis |
|---|
| Bridging the Gap: From Clinic to Home in IBD Monitoring-Authors' Reply. |
| Pancreatology |
| Event timing inaccuracies in a retrospective study of low-dose aspirin and acute pancreatitis. |
| Methodological Considerations Regarding "Prognostic impact of serum triglycerides in acute pancreatitis". |